Time in range (TIR) is an intuitive metric that denotes the amount of time in percentage that a person's glucose level remains within the proposed target range (3.9–10.0 mmol/L (3.5–7.8 mmol/L in pregnancy) or 70–180 mg/dL (63–140 mg/dL in pregnancy). The concept of TIR has emerged from the efforts of diabetes experts to discover a reliable parameter, “beyond HbA1c” to assess glycaemic control. According to the International consensus on time in range, TIR should be considered as the key CGM-derived metric defining short-time glycaemic control, since it delivers more actionable data than HbA1c alone. The panel also established specific target ranges identifying different diabetes populations such as pregnancy and high-risk groups. It was estimated that a type 1 or type 2 individual should spend more than 70% (16 h, 48 min) of a day in the target range while more than 50% (>12 h) is applicable for older and high-risk type 2 patients. An effective treatment should always target to increase TIR while reducing Time below range (TBR).

Unit 4,

Reference: Saboo B, Kesavadev J, Shankar A, et al. Time-in-range as a target in type 2 diabetes: An urgent need. Heliyon. 2021;7(1):e05967. Published 2021 Jan 15.