Endothelial dysfunction refers to a condition in which the endothelial cells that line the interior surface of blood vessels (the endothelium) are impaired or not functioning optimally. This dysfunction can lead to various cardiovascular problems and is considered an early marker of cardiovascular disease. Normally, healthy endothelial cells play a crucial role in maintaining vascular function, regulating blood flow, preventing blood clotting, and contributing to overall cardiovascular health.

Unit 7,

Reference: Medina-Leyte DJ, Zepeda-García O, Domínguez-Pérez M, González-Garrido A, Villarreal-Molina T, Jacobo-Albavera L. Endothelial Dysfunction, Inflammation and Coronary Artery Disease: Potential Biomarkers and Promising Therapeutical Approaches. Int J Mol Sci. 2021;22(8):3850. Published 2021 Apr 8.